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Refer to the following research papers
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The objective of this study is to validate an artificial intelligence (AI)–based fully automatic coronary artery calcium (CAC) scoring system on non-electrocardiogram (ECG)–gated low-dose chest computed tomography (LDCT) using multi-institutional datasets with manual CAC scoring as the reference standard.
The Coreline Soft Aview CAC, an AI-based automatic CAC scoring software to LDCT shows good to excellent reliability in CAC score and CAC severity categorization in multi-institutional datasets.
Young Joo Suh, Cherry Kim, June-Goo Lee, Hongmin Oh, Heejun Kang, Young-Hak Kim & Dong Hyun Yang. "Fully automatic coronary calcium scoring in non-ECG-gated low-dose chest CT: comparison with ECG-gated cardiac CT" European Radiology volume 33, pages1254–1265 (2023)


The objective of the current study was to evaluate the performance of deep learning–based software (CAC, Corelinesoft) for automatic coronary calcium scoring in a screening setting.
The deep learning–based software for automatic CAC scoring performed excellently in a population-based screening setting to determine risk categorization in asymptomatic participants.
Future deep learning software that is able to assign a limited number of uncertain cases for manual human feedback could improve the calcium scoring process and outperform (a panel of) experienced readers that solely use manual scoring.
Marleen Vonder PhD, Sunyi Zheng PhD, Monique D. Dorrius MD, PhD, Carlijn M. van der Aalst PhD, Harry J. de Koning MD, PhD, Jaeyoun Yi PhD, Donghoon Yu MSc, Jan Willem C. Gratama MD, PhD, Dirkjan Kuijpers MD, PhD, Matthijs Oudkerk MD, PhD "Deep Learning for Automatic Calcium Scoring in Population-Based Cardiovascular Screening" JACC: Cardiovascular Imaging Volume 15, Issue 2, February 2022, Pages 366-367

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