This study, published by the University of Parma team, investigated the feasibility of automated quantification of coronary artery calcification (CAC) and emphysema using low-dose (LDCT) and ultra-low-dose (ULDCT) CT scans in lung cancer screening. A total of 361 participants underwent scans analyzed with AVIEW software. The CAC measurements showed high agreement between LDCT and ULDCT (ICC = 0.86) with an overlap rate of 84%. In contrast, emphysema measurements exhibited moderate agreement (ICC = 0.57) and a tendency for overestimation on ULDCT. The findings demonstrate that ULDCT is suitable for CAC quantification and suggest the potential expansion of low-dose lung cancer screening into cardiovascular disease prevention. This study highlights the applicability of AVIEW software for CAC quantification even on ULDCT protocols.