In this comprehensive review article, the authors explore the technical advancements in quantitative CT imaging for assessing Chronic Obstructive Pulmonary Disease (COPD). They highlight the potential of quantitative imaging parameters in providing precise and objective assessments of COPD-related components, such as emphysema, small-airway disease, and comorbidities like pulmonary vessel alterations, atherosclerosis, cachexia, and osteoporosis. The authors discuss the association between these parameters and clinical measures of disease severity, respiratory symptoms, COPD exacerbations, and mortality, showcasing promising findings from various studies. Despite the optimistic results, the article also addresses the challenges hindering the integration of quantitative CT assessment into everyday COPD management. While the authors don't directly mention AVIEW software, they include numerous example screenshots throughout the article, indirectly illustrating the application and potential benefits of quantitative CT imaging in assessing COPD. The review provides insights into the current status, clinical implications, limitations, and future prospects of quantitative CT imaging in COPD assessment.